RFantibody

Generative antibody and nanobody design on RFdiffusion

RFantibody adapts RFdiffusion to antibody and nanobody design, scaffolding CDR loops onto designed frameworks for antigen-specific binding. It combines generative backbone diffusion with ProteinMPNN-style sequence design in one protocol. Enables de novo antibody discovery without prior binders or hybridomas.

RFantibody is being onboarded — request access and be first in line.