ANARCI
Antibody and TCR numbering across schemes
ANARCI aligns antibody and TCR variable domain sequences to hidden Markov models to number residues under IMGT, Kabat, Chothia, Martin and AHo schemes. It identifies germline genes and species of origin. Numbering is a prerequisite for CDR annotation, paratope analysis and antibody databases.
ANARCI is live on MolPilot — paste a sequence and press Fold.
At a glance
- Input
- Antibody or TCR sequences (FASTA)
- Output
- Numbered domains (CSV, FASTA)
- Developed by
- Oxford Protein Informatics Group
- Published
- Dunbar & Deane, Nucleic Acids Research 2016 · 2016
#numbering#annotation#cdr
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