Molecular render representing ABodyBuilder3

ABodyBuilder3

Paired Fv structure prediction from heavy and light sequences

ABodyBuilder3 predicts paired Fv structures from heavy- and light-chain sequences using scalable antibody-specific deep learning models building on ImmuneBuilder and ABodyBuilder2. It models CDR loops with improved accuracy over general structure predictors. Returns full-atom Fv models ready for docking and epitope analysis.

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At a glance

Input
Paired antibody sequences (FASTA)
Output
Fv structure (PDB)
Developed by
Oxford Protein Informatics Group
Published
Kenlay et al., Bioinformatics 2024 · 2024
#antibody-design#structure-prediction#cdr