TMalign
Structural alignment with TM-score
TMalign aligns two protein structures and reports TM-scores, RMSD and the optimal residue alignment independent of sequence similarity. TM-scores normalize by target length, enabling comparison across proteins of different sizes. Standard for evaluating prediction accuracy against reference structures.
TMalign is live on MolPilot — paste a sequence and press Fold.
At a glance
- Input
- Two structures (PDB)
- Output
- Alignment and TM-score (PDB)
- Developed by
- Zhang Lab
- Published
- Zhang & Skolnick, Nucleic Acids Research 2005 · 2005
#structural-alignment#tm-score#comparison
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