fpocket
Detect pockets and score druggability
fpocket identifies putative binding pockets on protein structures using Voronoi tessellation of alpha spheres and scores them for druggability and volume. It runs on a single PDB input within seconds. Commonly used to define docking sites and assess ligandability of targets.
fpocket is live on MolPilot — paste a sequence and press Fold.
At a glance
- Input
- Structure (PDB)
- Output
- Pocket predictions (PDB, TSV)
- Developed by
- Universite Paris Diderot
- Published
- Le Guilloux et al., 2009 · 2009
#pockets#druggability#binding-sites
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