HMMER
Sensitive profile-HMM sequence homology search
HMMER searches sequence databases using profile hidden Markov models, detecting remote homologs with sensitivity approaching structure-based methods. Profile-profile and profile-sequence searches run at practical speed using SIMD acceleration. The core engine behind Pfam and InterPro domain annotation.
HMMER is being onboarded — request access and be first in line.
At a glance
- Input
- Sequences or profiles (FASTA, HMM)
- Output
- Homology hits (tblout, domtblout)
- Developed by
- Eddy Lab
- Published
- Eddy, PLOS Computational Biology 2011 · 2011
#profile-hmm#homology-search#domains
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