Clustal Omega
Scalable MSA for hundreds of thousands of sequences
Clustal Omega aligns hundreds of thousands of sequences using seeded guide trees and hidden Markov profiles, scaling beyond classic progressive aligners. It handles large protein families and profile-profile alignment. The default aligner for bulk phylogenetic and family analysis pipelines.
Clustal Omega is being onboarded — request access and be first in line.
At a glance
- Input
- Sequences (FASTA)
- Output
- Multiple sequence alignment (FASTA)
- Developed by
- EMBL-EBI
- Published
- Sievers et al., Molecular Systems Biology 2011 · 2011
#alignment#msa#scalable
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