
DeepEMhancer
Sharpen and denoise cryo-EM maps with deep learning
DeepEMhancer post-processes cryo-EM density maps using a trained convolutional network that sharpens flexible regions while denoising background, mimicking expert map manipulation. It takes input maps and produces enhanced densities for model building. Improves interpretability of marginal-resolution regions.
DeepEMhancer is being onboarded — request access and be first in line.
At a glance
- Input
- Cryo-EM map (MRC, CCP4)
- Output
- Sharpened map (MRC)
- Developed by
- CNB-CSIC, Madrid
- Published
- Sanchez-Garcia et al., Communications Biology 2021 · 2020
#cryo-em#map-sharpening#post-processing
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