Molecular render representing Chai-1

Chai-1

Commercial-friendly AlphaFold3-class folding, MSA optional

Chai-1 is a multi-modal foundation model that predicts proteins, nucleic acids, small molecules, ions and their complexes from sequence inputs. It achieves accuracy comparable to AlphaFold3 while running single-sequence inference without MSAs when desired. Licensed to allow commercial use, making it a workhorse for industrial structure prediction.

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At a glance

Input
Sequences and ligands (FASTA, SDF)
Output
Predicted complex (PDB)
Developed by
Chai Discovery
Published
Chai Discovery, 2024 · 2024
#co-folding#commercial-friendly#msa-free