AlphaFlow

Generative conformational ensembles from sequence or structure

AlphaFlow frames structure prediction as a generative flow-matching process, producing diverse conformational ensembles rather than single structures. Starting from sequences or input backbones, it samples alternative states such as apo and holo forms. Useful for studying conformational change and seeding ensemble-based design.

AlphaFlow is being onboarded — request access and be first in line.