QEPPI
Drug-likeness index for PPI-targeting compounds
QEPPI computes a quantitative estimate index of drug-likeness specialized for compounds targeting protein-protein interactions, where classical Lipinski rules misjudge many actives. It scores molecules by physicochemical descriptor similarity to known PPI inhibitors. Helps triage PPI-focused libraries and prioritize non-classical chemotypes.
QEPPI is being onboarded — request access and be first in line.
At a glance
- Input
- Compounds (SMILES)
- Output
- QEPPI scores (CSV)
- Developed by
- Tokyo Institute of Technology
- Published
- Kosugi et al., 2021 · 2021
#drug-likeness#ppi#property-prediction
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