ColabDock

Restraint-guided protein-protein docking with AlphaFold2

ColabDock predicts protein-protein complex structures using an AlphaFold2-based network guided by user-provided restraints from crosslinking, mutagenesis or low-resolution experiments. It inverts the predictor into a docking optimizer that respects sparse structural constraints. Useful when unrestrained docking cannot discriminate between alternative interfaces.

ColabDock is being onboarded — request access and be first in line.